The CORE Group Polio Project (CGPP) is a multi-country, multi-partner initiative providing financial and technical support for strengthening host country efforts to eradicate polio, strengthen surveillance of zoonotic diseases, and control the spread of COVID-19. For over 20 years, this USAID flagship project, which initially only focused on polio eradication, has since used its infrastructure to expand to include the Global Health Security Agenda and COVID-19, dispelling misinformation in various regions and settings, with hard-to-reach, mobile, and under-served populations.This interactive session involving CGPP members from India, Horn of Africa, Ethiopia, and South Sudan will: * Identify common misinformation myths that have stalled or prevented immunizations for both human and animal health (One Health),* Distinguish urban and rural communication approaches to misinformation, * Involve participants to solve misinformation case studies * Share ideas on how to approach specific conversations around misinformation through role-play; and* Distribute a no-cost communication tools list